It’s hoped that if the procedure eventually works in humans, it could provide a more effective and less expensive alternative to weight-loss surgery, and reduce related health problems. The procedure, which still needs to be examined in humans, would place an “intestinal barrier sleeve” by endoscopy, which involves inserting a thin pipe through the mouth area into the tummy.
A flexible, nonpermeable silicone sleeve would be placed close to the end of the stomach, achieving to the first part of the small intestine. If desired, the tube could be removed by endoscopy at a later date. The study, released online Oct. 9 in the journal Gut, was a cooperation of German research workers and scientists at the University of Cincinnati. Like other weight-loss techniques, the intestinal barrier sleeve would work by stopping the absorption of calories and nutrients from the intestine. This technique is unique, however, since it doesn’t require surgery.
Kirk Habegger, co-lead writer of the study and an helper professor at the University of Cincinnati. Weight-loss surgery, such as gastric bypass, is more difficult, Habegger said. Bariatric surgery is made for severely obese people-commonly thought as those weighing at least 100 pounds more than is ideal for how old they are and height-who have been unsuccessful reducing your weight through diet, medication or exercise.
It works by physically restricting the amount of food people can eat or by interrupting the digestive process. For the study, tiny silicone intestinal barrier sleeves were crafted for rats and positioned surgically just inside the end of the stomach, increasing along the intestine near the ligament of Treitz, an anatomical landmark. The procedure was performed surgically, than by endoscopy rather, because doing endoscopy in rats is not feasible, Habegger said. Two groups of rats were compared: the ones that experienced the intestinal hurdle sleeves implanted and those that had surgery but did not have the hurdle sleeves placed. Body composition, blood sugar tolerance and bile acid levels were assessed before and after the method.
The researchers discovered that the intestinal hurdle sleeve significantly reduced body weight and improved the total amount between glucose (glucose) and extra fat. The info also showed that bile acids may come with an important role in reducing weight, a important clue to understanding the technicians of unwanted fat metabolism potentially, Habegger said. Why might the intestinal hurdle sleeve work? By putting the sleeve directly below the belly in the top part of the small intestine, Habegger said, the food-sensing and satiation triggers that exist in that area may be modified.
Although the findings of the new study are promising, researchers maintain that research regarding animals often does not produce similar results in humans. Research with humans is in the works: A physician not associated with this study said he’ll soon be involved as a principal investigator in a related clinical trial, testing the intestinal barrier sleeve in people.
Dr. Edward Phillips, vice chairman of the department of surgery and director of the Weight Loss Center at Cedars-Sinai Medical Center in LA. The likelihood of improving blood sugar metabolism-and the lower cost and threat of the procedure-would fit the needs of more patients, he said. The intestinal hurdle sleeve method could be done for people with Crohn’s disease and other illnesses that make them ineligible for gastric bypass surgery, Phillips said.
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But because the sleeve is made of silicone, those with latex allergy symptoms would most likely not have the ability to have the task, he added. Phillips said the intestinal barrier sleeve procedure would allow patients to avoid hospitalization rather than run the chance of perforation of the colon or death from anesthesia or surgery. The largest risk associated with the intestinal barrier sleeve is the chance that you won’t stay in place, Phillips said.
Even minor dehydration can lead to lack of energy, poor pores and skin, absence and constipation of concentration. It´s also just about the only drink that´s free, so no excuses never to the miracles of water there´s! While both black and green tea are calorie free and therefore ideal for weight loss, green tea extract containing caffeine and polyphenols have been found to cause thermogenesis and increase fat oxidation, which may increase metabolic rate slightly. Although it is unlikely to boost the speed enough to cause significant weight loss.
Green tea also boasts a sponsor of other benefits such as high levels of flavonoids, that are antioxidants that help fight cancer. Studies have also suggested that heart attack risk is reduced with regular intake of green tea. In moderation (maximum three to four 4 cups each day), black espresso has been proven to have beneficial results for the ongoing health.